Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TOP2A | P11388 | 5/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264180 | 0.94 | ADRB2 (0.54) | ADRB2STAT3KDM4EHPGDALDH1A1 | |
| SCHEMBL9265070 | 0.92 | ADRB2 (0.52) | ADRB2STAT3KDM4EHPGDALDH1A1 | |
| SCHEMBL9264733 | 0.91 | ADRB2 (0.51) | ADRB2STAT3KDM4EHPGDALDH1A1 | |
| SCHEMBL29492858 | 0.90 | ADRB2 (0.68) | ADRB2STAT3KDM4EHPGDALDH1A1 | |
| SCHEMBL2844967 | 0.90 | ADRB2 (0.68) | ADRB2STAT3KDM4EHPGDALDH1A1 | |
| SCHEMBL9264329 | 0.87 | ADRB2 (0.58) | ADRB2STAT3KDM4EHPGDALDH1A1 | |
| SCHEMBL9261876 | 0.86 | STAT3 (0.47) | ADRB2STAT3KDM4EHPGDALDH1A1 | |
| SCHEMBL9270695 | 0.86 | KMT2A (0.57) | ADRB2STAT3KDM4EHPGDALDH1A1 | |
| SCHEMBL9267912 | 0.84 | STAT3 (0.61) | ADRB2STAT3KDM4EHPGDALDH1A1 | |
| SCHEMBL8136160 | 0.84 | TOP2A (0.57) | KDM4EHPGDALDH1A1HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393400-B1 | Novel quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KK (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5245037-A | Synthetic bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0393400-A1 | Novel quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-24 | — | — | EP | disclosed |