Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.59 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9385049 | 0.94 | SLC22A2 (0.57) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9383710 | 0.89 | KCNH2 (0.64) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| Oxalic Acid SCHEMBL9385454 | 0.89 | SLC22A2 (0.59) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9384586 | 0.88 | KCNH2 (0.68) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| Hydrochloric Acid SCHEMBL9383350 | 0.87 | KCNH2 (0.67) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9870171 | 0.87 | KCNH2 (0.67) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9385096 | 0.85 | SLC22A2 (0.58) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| Oxalic Acid SCHEMBL9385689 | 0.85 | KCNH2 (0.61) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9386254 | 0.84 | KCNH2 (0.66) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL9383759 | 0.84 | ADRB1 (0.55) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |