SCHEMBL9385018

SCHEMBL9385018

CCCCCCCNC(=O)Oc1ccc2c(c1)C(Cl)N1CCCCCC1=N2

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 13/20 0.49
BCHE P06276 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8968475 0.79 ACHE (0.54) ACHEBCHE
SCHEMBL8968501 0.78 ACHE (0.52) ACHEBCHE
SCHEMBL8969539 0.72 ACHE (0.43) ACHE
SCHEMBL8969783 0.71 ACHE (0.42) ACHE
SCHEMBL8969967 0.70 ACHE (0.45) ACHE
SCHEMBL8968367 0.69 ACHE (0.40) ACHE
SCHEMBL8841980 0.69 ACHE (0.68) ACHE
SCHEMBL8969840 0.69 ACHE (0.43) ACHE
SCHEMBL8968329 0.68 ACHE (0.39) ACHE
SCHEMBL2405318 0.67 ACHE (0.58) ACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0365678-B1 2,5,6,7-TETRANOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND USE THEREOF TORAY INDUSTRIES (JP) 1994-01-05 EP disclosed
EP-0365678-A1 2,5,6,7-TETRANOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND USE THEREOF TORAY INDUSTRIES, INC. (JP) 1990-05-02 EP disclosed