⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300395 | 1.00 | — | — | |
| SCHEMBL7335309 | 1.00 | — | — | |
| SCHEMBL7334111 | 0.91 | TOP2A (0.32) | — | |
| SCHEMBL19067289 | 0.80 | TOP2A (0.30) | — | |
| SCHEMBL20946384 | 0.80 | TOP2A (0.30) | — | |
| SCHEMBL23670055 | 0.80 | — | — | |
| SCHEMBL19067292 | 0.80 | TOP2A (0.30) | — | |
| SCHEMBL5057553 | 0.80 | TOP2A (0.30) | — | |
| SCHEMBL23669704 | 0.80 | — | — | |
| SCHEMBL4760761 | 0.80 | TOP2A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399633-B1 | Leukotriene B4 derivatives, process for their preparation and their use as medicines | SCHERING AG (DE) | 1994-11-30 | — | — | EP | disclosed |
| US-5187286-A | LEUKOTRIENE-B4 DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICAL AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| WO-1990014329-A1 | LEUKOTRIENE B4 DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1990-11-29 | — | — | WO | disclosed |