Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | GALR1 | P47211 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968550 | 0.83 | ACHE (0.46) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969574 | 0.82 | ACHE (0.63) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968437 | 0.81 | ACHE (0.65) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969937 | 0.81 | ACHE (0.52) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8969106 | 0.79 | ACHE (0.63) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968700 | 0.79 | ACHE (0.70) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968436 | 0.79 | ACHE (0.70) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968767 | 0.77 | ACHE (0.68) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8968520 | 0.77 | ACHE (0.68) | ACHEBCHEMEN1USP2ALDH1A1 | |
| SCHEMBL8970192 | 0.76 | ACHE (0.70) | ACHEBCHEMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |