Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 4/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384834 | 0.88 | ALDH1A1 (0.42) | ALDH1A1GLAPKMTDP1VDR | |
| SCHEMBL9384517 | 0.82 | ALDH1A1 (0.37) | ALDH1A1GLAPKMTDP1VDR | |
| SCHEMBL4891492 | 0.81 | ALDH1A1 (0.49) | ALDH1A1GLAPKMTDP1VDR | |
| SCHEMBL9389579 | 0.79 | NQO2 (0.38) | ALDH1A1GLANQO2CYP19A1MAPT | |
| SCHEMBL10593702 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GLAPKMTDP1TP53 | |
| SCHEMBL10592466 | 0.76 | ALDH1A1 (0.44) | ALDH1A1GLAPKMTDP1VDR | |
| SCHEMBL6584403 | 0.76 | NQO2 (0.38) | ALDH1A1GLANQO2CYP19A1TSHR | |
| SCHEMBL9095651 | 0.75 | ALDH1A1 (0.43) | ALDH1A1NQO2CYP19A1TSHRCYP3A4 | |
| SCHEMBL12559831 | 0.75 | NQO2 (0.55) | ALDH1A1GLAPKMNQO2CYP19A1 | |
| SCHEMBL11863877 | 0.74 | ALDH1A1 (0.48) | ALDH1A1GLAPKMTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994003425-A2 | CARBOSTYRIL DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIA | SYNTEX (U.S.A.) INC. (US) | 1994-02-17 | — | — | WO | disclosed |