Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 17/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314219 | 0.81 | CASP1 (0.36) | CASP1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9699003 | 0.78 | CASP1 (0.40) | CASP1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9699010 | 0.78 | CASP1 (0.40) | CASP1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9697727 | 0.78 | CASP1 (0.40) | CASP1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10049737 | 0.78 | TDP1 (0.45) | CASP1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14265360 | 0.77 | SMN1; SMN2 (0.51) | CASP1SMN1; SMN2 | |
| SCHEMBL9387378 | 0.76 | CASP1 (0.38) | CASP1ALDH1A1MAPT | |
| SCHEMBL28287911 | 0.76 | TDP1 (0.40) | CASP1ALDH1A1MAPT | |
| SCHEMBL23558913 | 0.75 | CASP1 (0.36) | CASP1ALDH1A1MAPT | |
| SCHEMBL12307316 | 0.75 | CASP1 (0.39) | CASP1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394991-B1 | 1-Azabicyclo(3.2.0)Hept-2-Ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5102877-A | Carbapenicillin antibiotics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0394991-A1 | 1-Azabicyclo(3.2.0)Hept-2-Ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |