Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 10/20 | 1.00 |
| ▸ | TERT | O14746 | 1/20 | 1.00 |
| ▸ | UCHL3 | P15374 | 1/20 | 1.00 |
| ▸ | MAPK14 | Q16539 | 1/20 | 1.00 |
| ▸ | CDC25A | P30304 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22942075 | 1.00 | AKT1 (1.00) | AKT1TERTUCHL3MAPK14CDC25A | |
| SCHEMBL9407417 | 0.95 | AKT1 (0.90) | AKT1TERTUCHL3MAPK14CDC25A | |
| SCHEMBL29549430 | 0.85 | AKT1 (0.74) | AKT1TERTUCHL3MAPK14CDC25A | |
| SCHEMBL17789850 | 0.84 | AKT1 (0.72) | AKT1TERTUCHL3MAPK14CDC25A | |
| Perifosine SCHEMBL6075387 | 0.83 | AKT1 (0.71) | AKT1TERTUCHL3MAPK14CDC25A | |
| SCHEMBL14447963 | 0.83 | AKT1 (0.71) | AKT1TERTUCHL3MAPK14CDC25A | |
| SCHEMBL14447962 | 0.83 | AKT1 (0.71) | AKT1TERTUCHL3MAPK14CDC25A | |
| SCHEMBL14447952 | 0.83 | AKT1 (0.71) | AKT1TERTUCHL3MAPK14CDC25A | |
| SCHEMBL14447863 | 0.83 | AKT1 (0.71) | AKT1TERTUCHL3MAPK14CDC25A | |
| SCHEMBL14492081 | 0.82 | AKT1 (0.69) | AKT1TERTUCHL3MAPK14CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 15993 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12636376-B2 | Methods and compositions for use of growth factor antibodies in combination with non-tyrosine targeting kinase inhibitors | IN3BIO LTD. (BM) | 2026-05-26 | — | — | US | claimed |
| US-20260139320-A1 | StarTrace: A Multiplex Drug Testing Platform for Personalized Medicine | UNIV OF SOUTH CAROLINA (US) | 2026-05-21 | — | — | US | claimed |
| EP-4743565-A2 | CYTOKINE ENCODING LENTIVIRAL VECTORS AND USES THEREOF FOR MAKING TUMOR INFILTRATING LYMPHOCYTES | Iovance Biotherapeutics, Inc. (US) | 2026-05-20 | — | — | EP | claimed |
| CN-122028938-A | Pharmaceutical combination comprising an anti-CD 37 antibody maytansinoid conjugate and a BCL2 inhibitor or PI3K inhibitor | 德彪药业国际股份公司 | 2026-05-12 | — | — | CN | claimed |
| EP-3645742-B1 | ANTI-ROR1 ANTIBODIES AND METHODS OF MAKING AND USING THEREOF | SYSTIMMUNE INC (US) | 2026-04-29 | — | — | EP | claimed |
| EP-4732908-A2 | CANCER TREATMENT USING COMBINATIONS OF ERK AND RAF INHIBITORS | Biomed Valley Discoveries, Inc. (US) | 2026-04-29 | — | — | EP | claimed |
| US-20260109699-A1 | AZOLE DERIVATIVES AS SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2026-04-23 | — | — | US | claimed |
| EP-4363043-B1 | COMPOSITIONS FOR USE IN METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS | NOVOCURE GMBH (CH) | 2026-04-22 | — | — | EP | claimed |
| US-20260103461-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | OLEMA PHARMACEUTICALS INC (US) | 2026-04-16 | — | — | US | claimed |
| US-20260097028-A1 | Methods of Treating Myeloproliferative Neoplasms | KARTOS THERAPEUTICS INC (US) | 2026-04-09 | — | — | US | claimed |
| US-20050227266-A1 | Biomarker:compound correlations in cancer diagnosis and therapy | APPLIED GENOMICS, INC. | 2005-10-13 | — | — | US | claimed |
| WO-2005085863-A2 | BIOMARKER: COMPOUND CORRELATIONS IN CANCER DIAGNOSIS AND THERAPY | APPLIED GENOMICS, INC. (US) | 2005-09-15 | — | — | WO | claimed |
| WO-2005063278-A1 | SURFACE PROTECTION OF EXPOSED BIOLOGICAL TISSUES | BIOACTIVE POLYMERS AB (SE) | 2005-07-14 | — | — | WO | claimed |
| CN-1622811-A | Use of alkylphosphocholines for the preventative treatment of protozoan diseases | ZENTARIS AG (DE) | 2005-06-01 | — | — | CN | claimed |
| CN-1617744-A | Anti-tumor combination therapy comprising substituted acryloyl distamycin derivatives and protein kinase (serine/threonine kinase) inhibitors | PHARMACIA ITALIA SPA (IT) | 2005-05-18 | — | — | CN | claimed |
| EP-1461083-A1 | COMBINED THERAPY AGAINST TUMORS COMPRISING SUBSTITUTED ACRYLOYL DISTAMYCIN DERIVATIVES AND PROTEIN KINASE (SERINE/THREONINE KINASE) INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-09-29 | — | — | EP | claimed |
| US-20040097470-A1 | Use of alkylphosphocholines in combination with antitumor medications for the treatment of benign and malignant oncoses in humans and mammals | ZENTARIS GMBH (DE) | 2004-05-20 | — | — | US | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
| WO-2003055522-A1 | COMBINED THERAPY AGAINST TUMORS COMPRISING SUBSTITUTED ACRYLOYL DISTAMYCIN DERIVATIVES AND PROTEIN KINASE (SERINE/THREONINE KINASE) INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2003-07-10 | — | — | WO | claimed |
| EP-1135193-B1 | AGENTS PROVIDED FOR TREATING TUMORS, BASED ON LIPOSOMES, AND CONTAINING TAMOXIFEN | MAX DELBRUECK CENTRUM (DE) | 2002-10-30 | — | — | EP | claimed |