Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 13/20 | 0.90 |
| ▸ | TERT | O14746 | 1/20 | 0.90 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.90 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.90 |
| ▸ | CDC25A | P30304 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perifosine SCHEMBL93872 | 0.95 | AKT1 (1.00) | AKT1TERTUCHL3MAPK14CDC25A | |
| SCHEMBL22942075 | 0.95 | AKT1 (1.00) | AKT1TERTUCHL3MAPK14CDC25A | |
| SCHEMBL29549430 | 0.91 | AKT1 (0.74) | AKT1TERTUCHL3MAPK14CDC25A | |
| SCHEMBL14447874 | 0.85 | AKT1 (0.64) | AKT1TERTUCHL3MAPK14CDC25A | |
| SCHEMBL14447880 | 0.85 | AKT1 (0.64) | AKT1TERTUCHL3MAPK14CDC25A | |
| SCHEMBL14447873 | 0.85 | AKT1 (0.64) | AKT1TERTUCHL3MAPK14CDC25A | |
| SCHEMBL17789850 | 0.80 | AKT1 (0.72) | AKT1TERTUCHL3MAPK14CDC25A | |
| SCHEMBL14447925 | 0.79 | TERT (0.57) | AKT1TERTUCHL3MAPK14 | |
| SCHEMBL14447876 | 0.79 | TERT (0.57) | AKT1TERTUCHL3MAPK14 | |
| SCHEMBL14447963 | 0.79 | AKT1 (0.71) | AKT1TERTUCHL3MAPK14CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579939-A1 | Phospholipid derivatives | ASTA Medica Aktiengesellschaft (DE) | 1994-01-26 | — | — | EP | claimed |