Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.61 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.53 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389817 | 0.84 | NPC1 (0.67) | NPC1RAB9AGRIN1GRIN2BKCNH2 | |
| N-Desmethyldofetilide SCHEMBL7853191 | 0.84 | KCNH2 (0.64) | NPC1RAB9AGRIN1GRIN2BKCNH2 | |
| SCHEMBL14113144 | 0.83 | NPC1 (0.93) | NPC1RAB9AGRIN1GRIN2BKCNH2 | |
| SCHEMBL9733253 | 0.83 | NPC1 (0.69) | NPC1RAB9AGRIN1GRIN2BKCNH2 | |
| SCHEMBL12640606 | 0.80 | GRIN1 (0.82) | NPC1RAB9AGRIN1GRIN2BKCNH2 | |
| SCHEMBL12678490 | 0.80 | LMNA (0.81) | NPC1RAB9AKCNH2LMNAMAPK1 | |
| SCHEMBL12640605 | 0.79 | GRIN1 (0.76) | NPC1RAB9AGRIN1GRIN2BKCNH2 | |
| SCHEMBL7867119 | 0.79 | HTT (0.60) | NPC1RAB9AGRIN1GRIN2BLMNA | |
| SCHEMBL9123987 | 0.79 | NPC1 (0.69) | NPC1RAB9AGRIN1GRIN2BKCNH2 | |
| SCHEMBL9732793 | 0.79 | NPC1 (0.73) | NPC1RAB9AGRIN1GRIN2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994003425-A2 | CARBOSTYRIL DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIA | SYNTEX (U.S.A.) INC. (US) | 1994-02-17 | — | — | WO | disclosed |