Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 4/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD1 | P21728 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389579 | 0.85 | NQO2 (0.38) | NQO2CYP19A1ADRB2DRD2DRD1 | |
| SCHEMBL9389343 | 0.83 | HTR1D (0.42) | NQO2CYP19A1ADRB2DRD2DRD1 | |
| SCHEMBL11401085 | 0.82 | NQO2 (0.53) | NQO2CYP19A1ADRB2KDM4EHPGD | |
| SCHEMBL6584403 | 0.79 | NQO2 (0.38) | NQO2CYP19A1ADRB2DRD2DRD1 | |
| SCHEMBL9384834 | 0.78 | ALDH1A1 (0.42) | NQO2CYP19A1ADRB2KDM4EHPGD | |
| SCHEMBL2796720 | 0.76 | NQO2 (0.47) | NQO2CYP19A1KDM4EHPGDGPR84 | |
| SCHEMBL14438072 | 0.74 | NQO2 (0.61) | NQO2CYP19A1KDM4EHPGDALDH1A1 | |
| SCHEMBL11121058 | 0.74 | MAPT (0.43) | NQO2CYP19A1ADRB2KDM4EHPGD | |
| SCHEMBL9653621 | 0.73 | NQO2 (0.47) | NQO2CYP19A1ADRB2DRD2DRD1 | |
| SCHEMBL2171202 | 0.73 | NQO2 (0.47) | NQO2CYP19A1KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994003425-A2 | CARBOSTYRIL DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIA | SYNTEX (U.S.A.) INC. (US) | 1994-02-17 | — | — | WO | disclosed |