Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 13/20 | 0.59 |
| ▸ | AGTR2 | P50052 | 12/20 | 0.59 |
| ▸ | AGT | P01019 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385591 | 0.92 | AGTR1 (0.61) | AGTR1AGTR2AGT | |
| SCHEMBL9276766 | 0.91 | AGTR1 (0.57) | AGTR1AGTR2AGT | |
| SCHEMBL9276943 | 0.91 | AGTR1 (0.57) | AGTR1AGTR2AGT | |
| SCHEMBL7397795 | 0.91 | AGTR1 (0.53) | AGTR1AGTR2AGT | |
| SCHEMBL7303260 | 0.91 | AGTR1 (0.61) | AGTR1AGTR2AGT | |
| SCHEMBL7400468 | 0.90 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL14855449 | 0.90 | AGTR1 (0.62) | AGTR1AGTR2AGT | |
| SCHEMBL9277433 | 0.90 | AGTR1 (0.55) | AGTR1AGTR2AGT | |
| SCHEMBL14855413 | 0.89 | AGTR1 (0.59) | AGTR1AGTR2AGT | |
| SCHEMBL14855464 | 0.88 | AGTR1 (0.62) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310929-A | Hypotensive | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-05-10 | — | — | US | disclosed |
| WO-1994003435-A1 | PRODRUGS OF IMIDAZOLE CARBOXYLIC ACIDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-02-17 | — | — | WO | disclosed |