SCHEMBL9387992

SCHEMBL9387992

CC(C)(C)Cc1nc2[nH]c(=O)[nH]c(=O)c2n1CC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 1/20 0.36
DPP4 P27487 1/20 0.36
NOD1 Q9Y239 1/20 0.35
BRDT Q58F21 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9387781 0.85 GDA (0.34) GDADPP4NOD1BRDT
SCHEMBL9387974 0.82 GDA (0.38) GDADPP4NOD1BRDT
SCHEMBL9386888 0.81 GDA (0.37) GDADPP4NOD1BRDT
SCHEMBL9844556 0.70 NOD1 (0.44) GDADPP4NOD1
SCHEMBL3902925 0.69 KDM4E (0.46) GDADPP4NOD1
SCHEMBL9386098 0.67 GDA (0.57) GDABRDT
SCHEMBL21389576 0.66 GDA (0.40) GDADPP4NOD1BRDT
SCHEMBL23255513 0.65 NOD1 (0.40) GDADPP4NOD1
SCHEMBL3690781 0.64 GDA (0.36) GDADPP4NOD1BRDT
SCHEMBL27908390 0.64 NOD1 (0.37) GDADPP4NOD1BRDT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994000452-A1 7-NEOPENTYL XANTHINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM MALESCI ISTITUTO FARMACOBIOLOGICO S.P.A. (IT) 1994-01-06 WO disclosed