Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | PDE5A | O76074 | 2/20 | 0.51 |
| ▸ | PDE9A | O76083 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570527 | 0.82 | HSP90AA1 (0.54) | HSP90AA1MEN1CYP1A2KMT2AMAPT | |
| SCHEMBL4947575 | 0.81 | MAPT (0.50) | HSP90AA1MEN1CYP1A2KMT2AMAPT | |
| SCHEMBL4947819 | 0.80 | HSP90AA1 (0.49) | HSP90AA1MEN1CYP1A2KMT2AMAPT | |
| SCHEMBL8947414 | 0.80 | DAO (0.63) | TSHRNFKB1CYP2C19ALDH1A1HPGD | |
| SCHEMBL1519787 | 0.76 | TP53 (0.45) | CYP1A2MAPTCYP2C9CYP2C19NPSR1 | |
| SCHEMBL30167009 | 0.76 | MAPT (0.57) | HSP90AA1MEN1CYP1A2KMT2AMAPT | |
| SCHEMBL9382609 | 0.76 | DAO (0.63) | MEN1KMT2AKCNMA1ALDH1A1HPGD | |
| SCHEMBL640787 | 0.76 | MEN1 (0.56) | MEN1KMT2ACYP2C9BLMCA12 | |
| SCHEMBL21413056 | 0.76 | HSP90AA1 (0.57) | HSP90AA1MEN1CYP1A2KMT2AMAPT | |
| SCHEMBL640506 | 0.76 | DAO (0.39) | HSP90AA1MEN1CYP1A2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309423-B1 | New benzimidazoline-2-oxo-1-carboxylic acid derivatives useful as 5-ht receptor antagonists | BOEHRINGER INGELHEIM ITALIA (IT) | 1994-06-15 | — | — | EP | disclosed |
| EP-0309423-A2 | New benzimidazoline-2-oxo-1-carboxylic acid derivatives useful as 5-ht receptor antagonists | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1989-03-29 | — | — | EP | disclosed |