Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 2/20 | 0.43 |
| ▸ | PDE9A | O76083 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934104 | 0.91 | MEN1 (0.41) | MAPTHSP90AA1MEN1CYP1A2CYP3A4 | |
| SCHEMBL7230617 | 0.90 | HSP90AA1 (0.43) | MAPTHSP90AA1MEN1CYP1A2CYP3A4 | |
| SCHEMBL21464105 | 0.84 | DAO (0.52) | MEN1KMT2A | |
| SCHEMBL25275524 | 0.83 | DAO (0.54) | CYP1A2CYP3A4CYP2C19KCNMA1 | |
| SCHEMBL4950092 | 0.82 | KCNQ3 (0.42) | KMT2AKIF11 | |
| SCHEMBL640969 | 0.82 | GABRG2 (0.48) | — | |
| SCHEMBL4296595 | 0.82 | CDK1 (0.46) | MAPTPDE5APDE9A | |
| SCHEMBL318223 | 0.82 | LMNA (0.45) | MEN1KMT2ACA12CA9 | |
| SCHEMBL14934065 | 0.81 | MAOB (0.38) | HSP90AA1ALDH1A1 | |
| SCHEMBL9388153 | 0.81 | HSP90AA1 (0.60) | MAPTHSP90AA1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080076810-A1 | Benzoureas Having Anti-Diabetic Activity | MERCK SHARP & DOHME CORP. | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076810-A1 | Benzoureas Having Anti-Diabetic Activity | PPARD, PPARG, GPR119 | MAPT 4720/4885HSP90AA1 1093/4885MEN1 4832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.