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SCHEMBL9388339

SCHEMBL9388339

C#CCN(Cc1ccc2nc(C)n(COC(=O)C(C)(C)C)c(=O)c2c1)c1cccc(C(=O)O)c1-c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NAMPT P43490 10/20 0.44
▸ TYMS P04818 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9391647 0.93 NAMPT (0.43) NAMPTTYMS
SCHEMBL9366697 0.90 NAMPT (0.45) NAMPTTYMS
SCHEMBL9389115 0.90 NAMPT (0.36) NAMPT
SCHEMBL9388342 0.89 NAMPT (0.42) NAMPTTYMS
SCHEMBL9388293 0.88 NAMPT (0.45) NAMPTTYMS
SCHEMBL9848799 0.88 NAMPT (0.44) NAMPTTYMS
SCHEMBL9391653 0.86 NAMPT (0.41) NAMPTTYMS
SCHEMBL8490827 0.85 NAMPT (0.51) NAMPTTYMS
SCHEMBL9389148 0.83 — —
SCHEMBL8488360 0.82 NAMPT (0.40) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994007869-A1 QUINAZOLINE DERIVATIVES ZENECA LIMITED (GB) 1994-04-14 — — WO disclosed