Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.44 |
| ▸ | TYMS | P04818 | 5/20 | 0.41 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366697 | 0.94 | NAMPT (0.45) | NAMPTTYMS | |
| SCHEMBL9388339 | 0.88 | NAMPT (0.44) | NAMPTTYMS | |
| SCHEMBL9388293 | 0.85 | NAMPT (0.45) | NAMPTTYMS | |
| SCHEMBL8488936 | 0.83 | NAMPT (0.38) | NAMPT | |
| SCHEMBL9246347 | 0.83 | NAMPT (0.54) | NAMPTDHFR | |
| SCHEMBL8490827 | 0.82 | NAMPT (0.51) | NAMPTTYMS | |
| SCHEMBL8488360 | 0.82 | NAMPT (0.40) | NAMPT | |
| SCHEMBL9391647 | 0.81 | NAMPT (0.43) | NAMPTTYMS | |
| SCHEMBL9388342 | 0.81 | NAMPT (0.42) | NAMPTTYMS | |
| SCHEMBL8488726 | 0.81 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459730-A2 | Anti-tumour compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |