Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HRH2 | P25021 | 1/20 | 0.63 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.63 |
| ▸ | HTR2A | P28223 | 1/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.63 |
| ▸ | HTR2B | P41595 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL9388409 | 0.93 | TLR7 (0.61) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL13435161 | 0.92 | TLR7 (0.74) | TLR7PDE4DLMNAPOLBHRH2 | |
| Propionic Acid SCHEMBL6719538 | 0.87 | TLR7 (0.62) | TLR7PDE4DLMNAPOLBHRH2 | |
| Propionic Acid SCHEMBL6726615 | 0.85 | TLR7 (0.63) | TLR7PDE4DLMNAPOLBHRH2 | |
| Propionic Acid SCHEMBL6726633 | 0.81 | TLR7 (0.53) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL4830500 | 0.80 | TLR7 (0.72) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL29376434 | 0.80 | TLR7 (0.72) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL487883 | 0.80 | TLR7 (0.68) | TLR7PDE4DLMNAPOLBHRH2 | |
| Imiquimod SCHEMBL5262205 | 0.80 | TLR7 (0.88) | TLR7PDE4DLMNAPOLBHRH2 | |
| Butyric Acid SCHEMBL6730560 | 0.79 | TLR7 (0.60) | TLR7PDE4DLMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582581-A1 | 1-SUBSTITUTED, 2-SUBSTITUTED 1H-IMIDAZO 4,5-c]QUINOLIN-4-AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-02-16 | — | — | EP | disclosed |