Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13134034 | 0.79 | CYP1A2 (0.47) | CYP1A2DRD3KDM4EALDH1A1MAPT | |
| SCHEMBL30297855 | 0.78 | CYP1A2 (0.46) | CYP1A2KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL8873486 | 0.77 | CYP1A2 (0.48) | CYP1A2ACHEKDM4EALDH1A1MAPT | |
| SCHEMBL7261759 | 0.77 | CYP1A2 (0.39) | MAOBCYP1A2DRD3KDM4EALDH1A1 | |
| SCHEMBL8875255 | 0.77 | MAOB (0.51) | MAOBCYP1A2ACHEMEN1KMT2A | |
| SCHEMBL6520637 | 0.76 | CYP1A2 (0.47) | CYP1A2KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL11408828 | 0.76 | NTRK1 (0.52) | CYP1A2KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL31526985 | 0.76 | CYP1A2 (0.47) | CYP1A2KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL4950343 | 0.75 | ASAH1 (0.56) | CYP1A2DRD3ALDH1A1 | |
| SCHEMBL22649412 | 0.75 | CYP1A2 (0.43) | CYP1A2KDM4EALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994004485-A1 | LIGANDS FOR Ga-68 PET HEART APPLICATIONS | MALLINCKRODT MEDICAL, INC. (US) | 1994-03-03 | — | — | WO | disclosed |