Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 7/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9388552 | 0.77 | MAOB (0.44) | MAOBMEN1KMT2AL3MBTL1ACHE | |
| SCHEMBL6535650 | 0.76 | MEN1 (0.43) | MEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL10887987 | 0.76 | MAOB (0.82) | MAOBACHEBCHE | |
| SCHEMBL2036237 | 0.74 | L3MBTL1 (0.54) | MEN1KMT2AL3MBTL1ACHECYP1A2 | |
| SCHEMBL8011548 | 0.73 | MEN1 (0.50) | MEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL30660067 | 0.73 | MEN1 (0.50) | MEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL8131752 | 0.73 | MAOB (0.83) | MAOBL3MBTL1ACHEBCHE | |
| SCHEMBL8873486 | 0.72 | CYP1A2 (0.48) | MEN1KMT2AL3MBTL1ACHECYP1A2 | |
| SCHEMBL8398570 | 0.72 | MAOB (0.84) | MAOBL3MBTL1ACHEBCHE | |
| SCHEMBL4079545 | 0.71 | CYP1A2 (0.44) | MEN1KMT2AL3MBTL1ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679852-A | Process for the production of DTPA-monoamides of the central carboxylic acid and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |
| US-5676923-A | SOLUBLE, STABLE, ORGAN-SPECIFIC NUCLEAR MAGNETIC RESONANCE CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5676926-A | Process for the production of DTPA-tetraesters of terminal carboxylic acids | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5514810-A | Process for the production of DTPA-tetraesters of terminal carboxylic acids | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-05-07 | — | — | US | disclosed |