Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 11/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 10/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269685 | 0.95 | PPARG (0.41) | AGTR1AGTR2 | |
| SCHEMBL9392388 | 0.94 | AGTR1 (0.45) | AGTR1AGTR2ACHE | |
| SCHEMBL6499862 | 0.91 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL8107927 | 0.90 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9267995 | 0.90 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9280743 | 0.89 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9389302 | 0.89 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9388462 | 0.89 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9388549 | 0.89 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9389339 | 0.89 | AGTR1 (0.47) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994008990-A1 | N-ARYLHETEROARYLALKYL 1-PHENYL-IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1994-04-28 | — | — | WO | disclosed |