SCHEMBL9388982

SCHEMBL9388982

COC(=O)[C]1C=CC=CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.38
CA2 P00918 4/20 0.38
TSHR P16473 2/20 0.35
NPSR1 Q6W5P4 1/20 0.34
CA12 O43570 3/20 0.34
CA7 P43166 3/20 0.34
CA9 Q16790 3/20 0.34
CA14 Q9ULX7 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
MAPT P10636 3/20 0.34
LMNA P02545 4/20 0.33
KDM4E B2RXH2 2/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
NFKB1 P19838 1/20 0.33
XDH P47989 1/20 0.33
GFER P55789 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
FUT7 Q11130 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8193984 0.75
SCHEMBL11146316 0.73
SCHEMBL12978511 0.71 CHRM3 (0.34) CA1CA2TSHRNPSR1CA12
Acetic Acid Methyl Ester SCHEMBL28642344 0.68 ALDH1A1 (0.42) ALDH1A1
SCHEMBL12493386 0.67 TSHR (0.41) CA1CA2TSHRNPSR1CA12
SCHEMBL8947531 0.67
Bicarbonate SCHEMBL11493509 0.65 CHRM3 (0.37) CA1CA2TSHRCA12CA7
SCHEMBL27209677 0.65 TSHR (0.39) CA1CA2TSHRNPSR1CA12
SCHEMBL10607467 0.65
SCHEMBL7632368 0.65 CHRM3 (0.40) CA1CA2TSHRNPSR1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994011344-A1 SUBSTITUTED 3,4,5,6-TETRAHYDROPHTHALIMIDES FOR USE AS HERBICIDES AND/OR DEFOLIANTS OR DESICCANTS BASF AKTIENGESELLSCHAFT (DE) 1994-05-26 WO disclosed