Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 8/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 8/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 8/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 8/20 | 0.49 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.49 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.49 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.49 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.49 |
| ▸ | GRIK4 | Q16099 | 3/20 | 0.49 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9387650 | 0.84 | GRIN2D (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9389317 | 0.80 | GRIN2D (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9393393 | 0.80 | GRIN2D (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9392866 | 0.80 | GRIN2D (0.64) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9387691 | 0.79 | MAPT (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9389950 | 0.79 | GPR35 (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9389375 | 0.78 | GRIN2D (0.51) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9393306 | 0.78 | GRIN2D (0.54) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9393192 | 0.78 | GRIN2D (0.43) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8581554 | 0.77 | GRIN2D (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007500-A1 | 2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS | WEBER ECKARD (US) | 1994-04-14 | — | — | WO | disclosed |