SCHEMBL9389331

SCHEMBL9389331

CCCCCCCCCCCCC1CCNCC1

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GNAO1 P09471 13/20 0.61
GNAI3 P08754 12/20 0.56
GNAI1 P63096 12/20 0.56
CYP1A2 P05177 1/20 0.48
EPHX1 P07099 2/20 0.43
ITGB3 P05106 2/20 0.43
ITGA2B P08514 2/20 0.43
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7345197 1.00 GNAO1 (0.61) GNAO1GNAI3GNAI1CYP1A2EPHX1
SCHEMBL9383358 1.00 GNAO1 (0.61) GNAO1GNAI3GNAI1CYP1A2EPHX1
SCHEMBL9388856 1.00 GNAO1 (0.61) GNAO1GNAI3GNAI1CYP1A2EPHX1
SCHEMBL9384220 1.00 GNAO1 (0.61) GNAO1GNAI3GNAI1CYP1A2EPHX1
SCHEMBL9385204 1.00 GNAO1 (0.61) GNAO1GNAI3GNAI1CYP1A2EPHX1
SCHEMBL9388213 1.00 GNAO1 (0.61) GNAO1GNAI3GNAI1CYP1A2EPHX1
SCHEMBL5494333 1.00 GNAO1 (0.61) GNAO1GNAI3GNAI1CYP1A2EPHX1
Hydrochloric Acid SCHEMBL26090986 0.98 GNAO1 (0.64) GNAO1GNAI3GNAI1CYP1A2EPHX1
SCHEMBL1368752 0.98 GNAO1 (0.58) GNAO1GNAI3GNAI1CYP1A2EPHX1
Hydrochloric Acid SCHEMBL7645440 0.95 GNAO1 (0.61) GNAO1GNAI3GNAI1CYP1A2ITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0604494-A1 5-HT 4? RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1994-07-06 EP disclosed