SCHEMBL938973

SCHEMBL938973

C=C(OS(=O)(=O)c1ccc(C)cc1)S(=O)(=O)C(=C)OS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
GAA P10253 3/20 0.45
F2 P00734 3/20 0.43
PRSS1 P07477 3/20 0.43
PRSS2 P07478 3/20 0.43
PRSS3 P35030 3/20 0.43
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP13 P45452 1/20 0.42
CA12 O43570 1/20 0.42
CA3 P07451 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA5B Q9Y2D0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28003017 0.82 ALDH1A1 (0.52) ALDH1A1GAAF2PRSS1PRSS2
SCHEMBL4119814 0.81 ALDH1A1 (0.46) ALDH1A1GAAF2PRSS1PRSS2
SCHEMBL28867389 0.81 ALDH1A1 (0.46) ALDH1A1GAAF2PRSS1PRSS2
SCHEMBL6283149 0.79 ALDH1A1 (0.49) ALDH1A1GAAF2PRSS1PRSS2
SCHEMBL10588578 0.78 ALDH1A1 (0.43) ALDH1A1GAAF2PRSS1PRSS2
SCHEMBL493845 0.78 ALDH1A1 (0.47) ALDH1A1GAAF2PRSS1PRSS2
SCHEMBL10637725 0.78 ALDH1A1 (0.60) ALDH1A1GAAF2PRSS1PRSS2
SCHEMBL11661398 0.77 ALDH1A1 (0.42) ALDH1A1GAAF2PRSS1PRSS2
Ammonia Solution, Strong SCHEMBL9252460 0.77 ALDH1A1 (0.46) ALDH1A1GAAF2PRSS1PRSS2
SCHEMBL443434 0.76 ALDH1A1 (0.53) ALDH1A1GAAF2PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178585-B2 Solvent-free synthesis of soluble nanocrystals ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2012-05-15 US claimed
US-20110006269-A1 SOLVENT-FREE SYNTHESIS OF SOLUBLE NANOCRYSTALS ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2011-01-13 US claimed
EP-2227319-A2 SOLVENT-FREE SYNTHESIS OF SOLUBLE NANOCRYSTALS Advanced Technology Materials, Inc. (US) 2010-09-15 EP claimed
WO-2009065010-A2 SOLVENT-FREE SYNTHESIS OF SOLUBLE NANOCRYSTALS ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2009-05-22 WO claimed
US-8178585-B2 Solvent-free synthesis of soluble nanocrystals ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2012-05-15 US disclosed
US-20110006269-A1 SOLVENT-FREE SYNTHESIS OF SOLUBLE NANOCRYSTALS ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2011-01-13 US disclosed
EP-2227319-A2 SOLVENT-FREE SYNTHESIS OF SOLUBLE NANOCRYSTALS Advanced Technology Materials, Inc. (US) 2010-09-15 EP disclosed
WO-2009065010-A2 SOLVENT-FREE SYNTHESIS OF SOLUBLE NANOCRYSTALS ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2009-05-22 WO disclosed
US-7118727-B2 Method of making oxide particles GENERAL ELECTRIC COMPANY (US) 2006-10-10 US disclosed
US-20060133978-A1 Method of making crystalline inorganic particles GENERAL ELECTRIC COMPANY 2006-06-22 US disclosed
US-20040253174-A1 Method of making oxide particles GENERAL ELECTRIC COMPANY 2004-12-16 US disclosed