Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 6/20 | 0.65 |
| ▸ | DDO | Q99489 | 3/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.60 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007832 | 0.86 | DAO (0.65) | DAODDOKDM4EALDH1A1HPGD | |
| SCHEMBL9387730 | 0.79 | HPGD (0.60) | DAODDOKDM4EALDH1A1HPGD | |
| SCHEMBL9007825 | 0.79 | DAO (0.65) | DAOKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL9387632 | 0.79 | DAO (0.65) | DAODDOKDM4EALDH1A1HPGD | |
| SCHEMBL16767846 | 0.79 | DAO (1.00) | DAODDOKDM4EALDH1A1HPGD | |
| SCHEMBL9387925 | 0.79 | DAO (0.53) | DAODDO | |
| SCHEMBL3422670 | 0.77 | KDM4E (0.53) | DAODDOKEAP1NFE2L2KDM4E | |
| SCHEMBL2639080 | 0.77 | DAO (0.61) | DAODDOKDM4EALDH1A1HPGD | |
| SCHEMBL9393317 | 0.76 | FASN (0.57) | DAODDOMEN1KMT2A | |
| SCHEMBL9393070 | 0.76 | DAO (0.63) | DAODDOKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007500-A1 | 2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS | WEBER ECKARD (US) | 1994-04-14 | — | — | WO | disclosed |