Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9142314 | 0.88 | DPP4 (0.54) | DPP4DPP9DPP8LMNACYP2D6 | |
| SCHEMBL1889778 | 0.85 | DPP8 (0.47) | DPP4DPP9DPP8LMNACYP2D6 | |
| SCHEMBL1600752 | 0.82 | DPP4 (0.49) | DPP4DPP9DPP8LMNACYP2D6 | |
| SCHEMBL8991336 | 0.82 | DPP9 (0.53) | DPP4DPP9DPP8LMNACYP2D6 | |
| SCHEMBL28492009 | 0.81 | DPP4 (0.51) | DPP4DPP9DPP8LMNACYP2D6 | |
| SCHEMBL939991 | 0.81 | NOD1 (0.41) | DPP4DPP9DPP8GABRPGABRD | |
| SCHEMBL9273038 | 0.81 | DPP4 (0.48) | DPP4DPP9DPP8LMNACYP2D6 | |
| SCHEMBL1534386 | 0.80 | DPP4 (0.50) | DPP4DPP9DPP8LMNACYP2D6 | |
| SCHEMBL3240642 | 0.80 | DPP4 (0.50) | DPP4DPP9DPP8LMNACYP2D6 | |
| SCHEMBL1888867 | 0.79 | FOLH1 (0.47) | DPP4DPP9DPP8LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7869957-B2 | Methods and systems to identify operational reaction pathways | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-01-11 | — | — | US | disclosed |