Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL61250 | 0.79 | HTR2A (0.36) | RETHTR2AHTR6SIGMAR1KDM4E | |
| SCHEMBL8677599 | 0.79 | HTR2A (0.34) | RETHTR2AHTR6SIGMAR1KDM4E | |
| SCHEMBL29480066 | 0.79 | RET (0.38) | RETHTR2AHTR6SIGMAR1KDM4E | |
| SCHEMBL29697103 | 0.79 | HTR2A (0.38) | RETHTR2AHTR6SIGMAR1KDM4E | |
| SCHEMBL3685967 | 0.79 | HTR2A (0.38) | RETHTR2AHTR6SIGMAR1KDM4E | |
| SCHEMBL6857385 | 0.79 | RET (0.38) | RETHTR2AHTR6SIGMAR1KDM4E | |
| SCHEMBL7601167 | 0.78 | RET (0.39) | RETHTR2AHTR6SIGMAR1KDM4E | |
| Hydrochloric Acid SCHEMBL30074160 | 0.77 | HTR2A (0.37) | RETHTR2AHTR6SIGMAR1KDM4E | |
| Hydrochloric Acid SCHEMBL4457343 | 0.77 | KDM4E (0.40) | RETHTR2AHTR6SIGMAR1KDM4E | |
| SCHEMBL4451821 | 0.76 | HTR2A (0.34) | HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609483-A1 | ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY | Urigen Pharmaceuticals, Inc. (US) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018191412-A9 | ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY | URIGEN PHARMACEUTICALS, INC. (US) | 2019-05-31 | — | — | WO | disclosed |
| WO-2018191412-A1 | ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY | URIGEN PHARMACEUTICALS, INC. (US) | 2018-10-18 | — | — | WO | disclosed |
| US-8394737-B2 | Preparation of activating supports | TOTAL PETROCHEMICALS RESEARCH FELUY Seneffe (BE) | 2013-03-12 | — | — | US | disclosed |
| US-20110009582-A1 | Preparation of Activating Supports | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2011-01-13 | — | — | US | disclosed |
| EP-2170511-A1 | PREPARATION OF ACTIVATING SUPPORTS | Total Petrochemicals Research Feluy (BE) | 2010-04-07 | — | — | EP | disclosed |
| EP-2025403-A1 | Preparation of activating supports | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2009-02-18 | — | — | EP | disclosed |
| WO-2009013197-A1 | PREPARATION OF ACTIVATING SUPPORTS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2009-01-29 | — | — | WO | disclosed |
| US-5969049-A | Process for preparing propylene polymer composition and propylene polymer composition | MITSUI CHEMICALS, INC. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0469153-B1 | PROCESS FOR PRODUCING THERMOPLASTIC ELASTOMER | MITSUI PETROCHEMICAL IND (JP) | 1996-04-10 | — | — | EP | disclosed |
| US-5300581-A | Melting and kneading mixture of polymer particles, graft modifier and radical initiator | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5126301-A | Organometallic compound, aluminoxane, group 4 metal compound, and olefin polymer | MITSUI PETROCHEMICAL INDUSTRIES, INC. (JP) | 1992-06-30 | — | — | US | disclosed |
| EP-0469153-A1 | PROCESS FOR PRODUCING THERMOPLASTIC ELASTOMER | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |
| EP-0427567-A2 | Parabolic antenna reflector and process for preparing same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| EP-0406912-A2 | Process for polymerizing olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |
| EP-0294942-A1 | Solid catalyst for polymerizing an olefin | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-12-14 | — | — | EP | disclosed |
| EP-0285443-A1 | Process for producing solid catalyst for polymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-10-05 | — | — | EP | disclosed |
| EP-0283164-A2 | Cyclo-olefinic random copolymer, olefinic random copolymer, and process for producing cyclo-olefinic random copolymers | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |