SCHEMBL4451821

SCHEMBL4451821

[CH2]C[Zr](CCl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.34
HTR6 P50406 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8677599 0.83 HTR2A (0.34) HTR2AHTR6
SCHEMBL9220624 0.81 SIGMAR1 (0.36) HTR2AHTR6
SCHEMBL4453745 0.76 HTR6 (0.35) HTR2AHTR6
Ethylene SCHEMBL819259 0.76 HTR2A (0.36) HTR2AHTR6
SCHEMBL939102 0.76 RET (0.37) HTR2AHTR6
SCHEMBL5705527 0.75 HTR2A (0.35) HTR2AHTR6
SCHEMBL9064184 0.73 HTR2A (0.35) HTR2AHTR6
Ethylene SCHEMBL2231954 0.73 HTR2A (0.35) HTR2AHTR6
SCHEMBL6055286 0.72 SIGMAR1 (0.39) HTR2AHTR6
SCHEMBL29479999 0.72 SIGMAR1 (0.39) HTR2AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7531605-B2 Process for producing polyolefin resin composition and polypropylene composition IDEMITSU KOSAN CO., LTD. (JP) 2009-05-12 US disclosed
EP-1375538-B1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU KOSAN CO (JP) 2008-01-09 EP disclosed
US-20040106738-A1 Process for producing polyolefin resin composition and polypropylene composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-06-03 US disclosed
EP-1375538-A1 PROCESS FOR PRODUCING POLYOLEFIN RESIN COMPOSITION AND POLYPROPYLENE COMPOSITION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-01-02 EP disclosed