Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 15/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.53 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391534 | 0.89 | OPRK1 (0.61) | OPRK1OPRM1OPRD1CYP2D6CCR5 | |
| SCHEMBL9389652 | 0.85 | OPRK1 (0.56) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL9394779 | 0.81 | OPRK1 (0.60) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL19739293 | 0.80 | OPRK1 (0.47) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL17883719 | 0.80 | OPRK1 (0.47) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL19739344 | 0.80 | OPRK1 (0.47) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL9391026 | 0.79 | OPRK1 (0.46) | OPRK1OPRM1OPRD1CYP2D6CCR5 | |
| SCHEMBL19753587 | 0.78 | OPRK1 (0.47) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL19739155 | 0.73 | OPRK1 (0.46) | OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL17883716 | 0.73 | OPRK1 (0.46) | OPRK1OPRM1OPRD1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994018165-A1 | SULFONAMIDE COMPOUNDS AS OPIOID K-RECEPTOR AGONISTS | PFIZER INC. (US) | 1994-08-18 | — | — | WO | disclosed |