Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002920 | 0.87 | — | — | |
| SCHEMBL9394694 | 0.86 | PAOX (0.36) | KMT2ACYP1A2CYP2C19SQORMEN1 | |
| SCHEMBL9116975 | 0.86 | PAOX (0.36) | KMT2ACYP1A2CYP2C19SQORMEN1 | |
| SCHEMBL6944697 | 0.86 | MAPT (0.37) | KMT2AMEN1GAAMAPK10CYP2C9 | |
| SCHEMBL1822007 | 0.85 | PAOX (0.34) | KMT2ACYP1A2CYP2C19MEN1GAA | |
| SCHEMBL8802577 | 0.85 | MAPK10 (0.38) | KMT2ACYP1A2CYP2C19MEN1GAA | |
| SCHEMBL8803670 | 0.84 | TK1 (0.43) | KMT2ACYP1A2CYP2C19MEN1GAA | |
| SCHEMBL8644267 | 0.84 | CYP2C19 (0.38) | KMT2ACYP1A2CYP2C19SQORMEN1 | |
| SCHEMBL8651289 | 0.84 | CYP2C19 (0.38) | KMT2ACYP1A2CYP2C19SQORMEN1 | |
| SCHEMBL8952586 | 0.82 | KDM4E (0.36) | KMT2AMEN1GAAMAPK10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994016704-A1 | OXIME-SUBSTITUTED THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-08-04 | — | — | WO | disclosed |