Ethylene Glycol

Ethylene Glycol

SCHEMBL939240

CCCCCCCCc1ccccc1OP(=O)(O)O.OCCO

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.52
THRB P10828 1/20 0.52
PPARA Q07869 2/20 0.47
LIPG Q9Y5X9 1/20 0.46
ALOX5 P09917 1/20 0.46
PTGS2 P35354 1/20 0.46
PPARG P37231 1/20 0.45
PLK1 P53350 1/20 0.43
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
HTR2B P41595 1/20 0.41
CETP P11597 3/20 0.41
S1PR2 O95136 1/20 0.41
S1PR4 O95977 1/20 0.41
S1PR1 P21453 1/20 0.41
S1PR3 Q99500 1/20 0.41
ENPP2 Q13822 1/20 0.41
BID P55957 2/20 0.40
BCL2L1 Q07817 2/20 0.40
MCL1 Q07820 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL28721591 1.00 THRA (0.52) THRATHRBPPARALIPGALOX5
SCHEMBL18141467 0.96 THRA (0.56) THRATHRBPPARALIPGALOX5
SCHEMBL10878272 0.96 THRA (0.56) THRATHRBPPARALIPGALOX5
SCHEMBL4446004 0.96 THRA (0.56) THRATHRBPPARALIPGALOX5
SCHEMBL18140912 0.96 THRA (0.56) THRATHRBPPARALIPGALOX5
SCHEMBL248072 0.96 THRA (0.56) THRATHRBPPARALIPGALOX5
SCHEMBL18141719 0.96 THRA (0.56) THRATHRBPPARALIPGALOX5
SCHEMBL1100816 0.96 THRA (0.56) THRATHRBPPARALIPGALOX5
SCHEMBL18140210 0.96 THRA (0.56) THRATHRBPPARALIPGALOX5
SCHEMBL18139782 0.96 THRA (0.56) THRATHRBPPARALIPGALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1996660-B1 INKJET INK COMPOSITION HEWLETT PACKARD DEVELOPMENT CO (US) 2010-01-06 EP claimed
US-7872060-B2 Inkjet ink composition HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2011-01-18 US disclosed
EP-1996660-B1 INKJET INK COMPOSITION HEWLETT PACKARD DEVELOPMENT CO (US) 2010-01-06 EP disclosed
EP-1996660-A2 INKJET INK COMPOSITION Hewlett-Packard Development Company, L.P. (US) 2008-12-03 EP disclosed
WO-2007112244-A2 INKJET INK COMPOSITION HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2007-10-04 WO disclosed
US-20070225400-A1 Inkjet ink composition HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2007-09-27 US disclosed