Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197799 | 1.00 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DABCB1 | |
| SCHEMBL9192977 | 0.81 | EGFR (0.33) | ABCC9MALT1KDM4E | |
| SCHEMBL9192982 | 0.81 | EGFR (0.33) | ABCC9MALT1KDM4E | |
| SCHEMBL9194996 | 0.78 | KDM4E (0.36) | PDE4APDE4BPDE4CPDE4DABCB1 | |
| SCHEMBL9194991 | 0.78 | KDM4E (0.36) | PDE4APDE4BPDE4CPDE4DABCB1 | |
| SCHEMBL9397178 | 0.76 | ABCB1 (0.33) | PDE4APDE4BPDE4CPDE4DABCB1 | |
| SCHEMBL9765392 | 0.76 | KDM4E (0.33) | PDE4APDE4BPDE4CPDE4DABCB1 | |
| SCHEMBL9397182 | 0.76 | ABCB1 (0.33) | PDE4APDE4BPDE4CPDE4DABCB1 | |
| SCHEMBL9765395 | 0.76 | KDM4E (0.33) | PDE4APDE4BPDE4CPDE4DABCB1 | |
| SCHEMBL9550599 | 0.76 | KDM4E (0.43) | PDE4APDE4BPDE4CPDE4DABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3279378-A | — | — | None | — | — | JP | disclosed |
| EP-0412531-B1 | Benzopyran compounds, processes for their production and pharmaceutical compositions | KAKEN PHARMA CO LTD (JP) | 1994-05-11 | — | — | EP | disclosed |
| JP-H03279378-A | BENZOPYRAN DERIVATIVE | KAKEN PHARMACEUT CO LTD | 1991-12-10 | — | — | JP | disclosed |
| EP-0412531-A1 | Benzopyran compounds, processes for their production and pharmaceutical compositions | Kaken Pharmaceutical Co., Ltd. (JP) | 1991-02-13 | — | — | EP | disclosed |