Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 12/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397182 | 1.00 | ABCB1 (0.33) | ABCB1KDM4EABCC9PDE4APDE4B | |
| SCHEMBL9194991 | 0.86 | KDM4E (0.36) | ABCB1KDM4EABCC9PDE4APDE4B | |
| SCHEMBL9194996 | 0.86 | KDM4E (0.36) | ABCB1KDM4EABCC9PDE4APDE4B | |
| SCHEMBL9765392 | 0.84 | KDM4E (0.33) | ABCB1KDM4EABCC9PDE4APDE4B | |
| SCHEMBL9765395 | 0.84 | KDM4E (0.33) | ABCB1KDM4EABCC9PDE4APDE4B | |
| SCHEMBL9394916 | 0.83 | ABCB1 (0.34) | ABCB1KDM4EABCC9PDE4APDE4B | |
| SCHEMBL9394910 | 0.83 | KCNE1 (0.35) | ABCB1KDM4EABCC9PDE4APDE4B | |
| SCHEMBL9197648 | 0.83 | ABCB1 (0.34) | ABCB1KDM4EABCC9PDE4APDE4B | |
| SCHEMBL9194763 | 0.83 | KCNE1 (0.35) | ABCB1KDM4EABCC9PDE4APDE4B | |
| SCHEMBL10515061 | 0.83 | ABCB1 (0.36) | ABCB1KDM4EABCC9PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412531-B1 | Benzopyran compounds, processes for their production and pharmaceutical compositions | KAKEN PHARMA CO LTD (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5095016-A | Hypotensive | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1992-03-10 | — | — | US | disclosed |
| EP-0412531-A1 | Benzopyran compounds, processes for their production and pharmaceutical compositions | Kaken Pharmaceutical Co., Ltd. (JP) | 1991-02-13 | — | — | EP | disclosed |