Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 4/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22263115 | 0.86 | GPR3 (0.46) | CNR2CNR1LOXL2GPR3HRH1 | |
| SCHEMBL14045624 | 0.86 | CNR2 (0.46) | CNR2CNR1LOXL2GPR3HRH1 | |
| SCHEMBL12848845 | 0.82 | PLK1 (0.37) | CNR2CNR1LOXL2GPR3HRH1 | |
| SCHEMBL13352406 | 0.77 | CNR2 (0.45) | CNR2CNR1LOXL2GPR3PTPN1 | |
| SCHEMBL9393961 | 0.76 | MAPT (0.40) | L3MBTL1KDM4E | |
| SCHEMBL717815 | 0.76 | CNR2 (0.34) | CNR2CNR1LOXL2HRH1CYP2D6 | |
| SCHEMBL23132153 | 0.75 | GPR3 (0.46) | LOXL2GPR3HRH1CYP2D6CHRM1 | |
| SCHEMBL31499102 | 0.75 | GPR3 (0.46) | LOXL2GPR3HRH1CYP2D6CHRM1 | |
| SCHEMBL2388976 | 0.75 | CNR2 (0.46) | CNR2CNR1LOXL2GPR3PTPN1 | |
| SCHEMBL11321079 | 0.74 | NPY1R (0.49) | CNR2CNR1LOXL2GPR3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027985-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-HALOMETHYL-BENZOTHIOPHENES, BENZOFURANS AND -INDOLES AND INTERMEDIATES THEREOF | SMITHKLINE BEECHAM CORPORATION (US) | 1994-12-08 | — | — | WO | disclosed |