Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.60 |
| ▸ | PI4KA | P42356 | 2/20 | 0.60 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.60 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.60 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.60 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.60 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.60 |
| ▸ | GAPDH | P04406 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | STAT6 | P42226 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.60 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9394642 | 1.00 | ADORA3 (0.60) | ADORA3ADORA2AADORA2BPI4KAPI4K2B | |
| SCHEMBL9393765 | 0.89 | ADORA3 (0.60) | ADORA3ADORA2AADORA2BPI4KAPI4K2B | |
| SCHEMBL9393769 | 0.89 | ADORA3 (0.60) | ADORA3ADORA2AADORA2BPI4KAPI4K2B | |
| SCHEMBL8807365 | 0.84 | ADORA3 (0.62) | ADORA3ADORA2AADORA2BPI4KAPI4K2B | |
| SCHEMBL30870546 | 0.84 | ADORA3 (0.62) | ADORA3ADORA2AADORA2BPI4KAPI4K2B | |
| SCHEMBL8807358 | 0.84 | ADORA3 (0.62) | ADORA3ADORA2AADORA2BPI4KAPI4K2B | |
| SCHEMBL9397420 | 0.83 | ADORA3 (0.58) | ADORA3ADORA2AADORA2BPI4KAPI4K2B | |
| SCHEMBL9397412 | 0.83 | ADORA3 (0.58) | ADORA3ADORA2AADORA2BPI4KAPI4K2B | |
| SCHEMBL9397425 | 0.83 | ADORA3 (0.58) | ADORA3ADORA2AADORA2BPI4KAPI4K2B | |
| SCHEMBL9397365 | 0.81 | ADORA3 (0.58) | ADORA3ADORA2AADORA2BPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365849-B1 | Novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl adenosine derivatives | MERRELL DOW PHARMA (US) | 1994-09-14 | — | — | EP | disclosed |
| EP-0365849-A2 | Novel 2'-halomethylidene, 2'-ethenylidene and 2'-ethynyl adenosine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-05-02 | — | — | EP | disclosed |