Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9394694 | 1.00 | PAOX (0.36) | PAOXCYP2C9KMT2AMAPTRXFP1 | |
| SCHEMBL9116975 | 1.00 | PAOX (0.36) | PAOXCYP2C9KMT2AMAPTRXFP1 | |
| SCHEMBL1822007 | 0.99 | PAOX (0.34) | PAOXCYP2C9KMT2AMAPTRXFP1 | |
| SCHEMBL9392011 | 0.86 | KMT2A (0.38) | CYP2C9KMT2AMAPTMAPK1CYP1A2 | |
| SCHEMBL8952586 | 0.85 | KDM4E (0.36) | CYP2C9KMT2AMAPTMAPK1LMNA | |
| SCHEMBL8952620 | 0.85 | KDM4E (0.36) | CYP2C9KMT2AMAPTMAPK1LMNA | |
| SCHEMBL8952508 | 0.85 | KDM4E (0.36) | CYP2C9KMT2AMAPTMAPK1LMNA | |
| SCHEMBL8952638 | 0.85 | KDM4E (0.36) | CYP2C9KMT2AMAPTMAPK1LMNA | |
| SCHEMBL8002920 | 0.85 | — | — | |
| SCHEMBL5093692 | 0.85 | PDE4A (0.34) | PAOXCYP2C9KMT2AMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994016704-A1 | OXIME-SUBSTITUTED THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-08-04 | — | — | WO | disclosed |