Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 3/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9395168 | 1.00 | SRD5A1 (0.53) | SRD5A1SRD5A2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9395157 | 1.00 | SRD5A1 (0.53) | SRD5A1SRD5A2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9390039 | 0.87 | SRD5A1 (0.57) | SRD5A1SRD5A2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9390046 | 0.87 | SRD5A1 (0.57) | SRD5A1SRD5A2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9390050 | 0.87 | SRD5A1 (0.57) | SRD5A1SRD5A2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9391423 | 0.85 | SRD5A1 (0.51) | SRD5A1SRD5A2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9391430 | 0.85 | SRD5A1 (0.51) | SRD5A1SRD5A2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9391442 | 0.85 | SRD5A1 (0.51) | SRD5A1SRD5A2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7566749 | 0.82 | CYP11B2 (0.50) | SRD5A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7566745 | 0.82 | CYP11B2 (0.50) | SRD5A1CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026692-A1 | BICYCLIC AMIDE DERIVATIVES AND THEIR USE AS MUSCLE RELAXANTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-24 | — | — | WO | disclosed |