Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397029 | 0.84 | HTR2B (0.45) | HRH1SIGMAR1HDAC6HTR2B | |
| SCHEMBL992242 | 0.80 | HTR2B (0.58) | HRH1KCNH2CHRNA7SIGMAR1HTR2B | |
| SCHEMBL28562183 | 0.71 | HRH1 (0.49) | HRH1KCNH2CHRNA7HTR2B | |
| SCHEMBL993093 | 0.70 | HTR2B (0.55) | HRH1KCNH2CHRNA7HTR2B | |
| SCHEMBL8296045 | 0.70 | HTR2B (0.73) | HTR2B | |
| SCHEMBL14916479 | 0.70 | KCNH2 (0.51) | HRH1KCNH2CHRNA7HTR2B | |
| SCHEMBL28050009 | 0.69 | HTR2B (0.49) | HRH1KCNH2CHRNA7HTR2B | |
| SCHEMBL17023774 | 0.68 | HRH1 (0.79) | HRH1KCNH2HTR2B | |
| SCHEMBL21815504 | 0.67 | HTR2B (0.47) | HRH1KCNH2CHRNA7HTR2B | |
| Alinastine SCHEMBL142547 | 0.67 | HRH1 (1.00) | HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322850-A | Antiallergic piperidine derivatives of benzimidazole | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (ES) | 1994-06-21 | — | — | US | claimed |