Methacrylic Acid

Methacrylic Acid

SCHEMBL9397155

C=C(C)C(=O)O.C=C(C)C(=O)O.CC(C)CO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
TGFBR1 P36897 1/20 0.45
TDP1 Q9NUW8 3/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
RNPEP Q9H4A4 1/20 0.33
OR51E2 Q9H255 1/20 0.33
SLC7A5 Q01650 1/20 0.33
TET2 Q6N021 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL3647938 1.00 TSHR (0.50) TSHRTGFBR1TDP1ALDH1A1CYP2D6
Methacrylic Acid SCHEMBL5683702 1.00 TSHR (0.50) TSHRTGFBR1TDP1ALDH1A1CYP2D6
Methacrylic Acid SCHEMBL5463979 0.86 TDP1 (0.53) TSHRTGFBR1TDP1ALDH1A1OR51E2
Methacrylic Acid SCHEMBL9779539 0.86 TGFBR1 (0.43) TSHRTGFBR1TDP1ALDH1A1OR51E2
Methacrylic Acid SCHEMBL4653322 0.86 TDP1 (0.53) TSHRTGFBR1TDP1ALDH1A1OR51E2
Methacrylic Acid SCHEMBL3319371 0.86 TGFBR1 (0.43) TSHRTGFBR1TDP1ALDH1A1OR51E2
Methacrylic Acid SCHEMBL5462229 0.86 TDP1 (0.53) TSHRTGFBR1TDP1ALDH1A1OR51E2
Methacrylic Acid SCHEMBL18140227 0.86 TDP1 (0.53) TSHRTGFBR1TDP1ALDH1A1OR51E2
Methacrylic Acid SCHEMBL475891 0.86 TDP1 (0.53) TSHRTGFBR1TDP1ALDH1A1OR51E2
Methacrylic Acid SCHEMBL2059838 0.86 TDP1 (0.53) TSHRTGFBR1TDP1ALDH1A1OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5374682-A Hard, acid resistant automobile topcoatings NIPPON PAINT CO., LTD. (JP) 1994-12-20 US disclosed
EP-0250183-B1 COATING POWDER Nippon Paint Co., Ltd. (JP) 1993-09-22 EP disclosed
EP-0217385-B1 METHOD OF FORMING METALLIC COATINGS Nippon Paint Co., Ltd. (JP) 1991-01-02 EP disclosed
EP-0250183-A2 Coating powder Nippon Paint Co., Ltd. (JP) 1987-12-23 EP disclosed