Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 16/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753749 | 0.82 | HDAC1 (0.59) | BRD4KDM4EKMT2AL3MBTL1 | |
| SCHEMBL22230076 | 0.77 | PARP1 (0.53) | PARP1KDM4EBLMALDH1A1LMNA | |
| SCHEMBL29532188 | 0.77 | PARP1 (0.53) | PARP1KDM4EBLMALDH1A1LMNA | |
| SCHEMBL12668594 | 0.77 | P2RX7 (0.58) | — | |
| SCHEMBL1893432 | 0.76 | KDM4E (0.65) | PARP1KDM4EBLMALDH1A1LMNA | |
| SCHEMBL1897417 | 0.76 | P2RX7 (0.57) | — | |
| SCHEMBL2521184 | 0.74 | PARP1 (0.58) | PARP1KDM4EBLMALDH1A1LMNA | |
| SCHEMBL2117675 | 0.74 | PLK1 (0.66) | BRD4ALDH1A1HPGDRAB9AMEN1 | |
| SCHEMBL23985232 | 0.73 | HDAC1 (0.59) | KDM4EALDH1A1LMNAHPGDRAB9A | |
| SCHEMBL31483721 | 0.71 | HTT (0.64) | BRD4ALDH1A1HPGDKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027969-A1 | ISOQUINOLINETRIONE DERIVATIVES AS HERBICIDES | ZENECA LIMITED (GB) | 1994-12-08 | — | — | WO | disclosed |