Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | C1R | P00736 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360865 | 0.83 | TDP1 (0.46) | ALDH1A1TDP1KMT2AMAPTMEN1 | |
| SCHEMBL30535903 | 0.80 | ALDH1A1 (0.74) | ALDH1A1TDP1KMT2AMEN1PTPN1 | |
| SCHEMBL1287837 | 0.80 | ALDH1A1 (0.74) | ALDH1A1TDP1KMT2AMEN1PTPN1 | |
| SCHEMBL5557695 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TDP1KMT2AMAPTMEN1 | |
| SCHEMBL30987815 | 0.78 | ALDH1A1 (0.71) | ALDH1A1TDP1KMT2AMEN1PTPN1 | |
| Ammonia Solution, Strong SCHEMBL9060371 | 0.78 | ALDH1A1 (0.71) | ALDH1A1TDP1MAOBKMT2AMEN1 | |
| SCHEMBL29337140 | 0.78 | ALDH1A1 (0.71) | ALDH1A1TDP1KMT2AMEN1PTPN1 | |
| SCHEMBL9017956 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TDP1MAOBKMT2AMAPT | |
| SCHEMBL30798624 | 0.73 | ALDH1A1 (0.59) | ALDH1A1TDP1MAOBKMT2AMAPT | |
| SCHEMBL944371 | 0.73 | ALDH1A1 (0.59) | ALDH1A1TDP1MAOBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250566-A | Using nitrophenyl pyrones derived from streptomyces | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1993-10-05 | — | — | US | claimed |
| US-5236949-A | Exposing to nitrophenyl pyrone | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1993-08-17 | — | — | US | claimed |
| WO-1993012656-A1 | METHOD FOR CONTROLLING INSECTS | MICHIGAN STATE UNIVERSITY (US) | 1993-07-08 | — | — | WO | claimed |
| US-5360918-A | Griseulin; larvicides, nematocides; mosquitoes | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1994-11-01 | — | — | US | disclosed |
| US-5310754-A | Nirtophenyl pyrones; nemetocides; effective against mosquito larvae | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1994-05-10 | — | — | US | disclosed |
| US-5250566-A | Using nitrophenyl pyrones derived from streptomyces | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1993-10-05 | — | — | US | disclosed |
| US-5236949-A | Exposing to nitrophenyl pyrone | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) | 1993-08-17 | — | — | US | disclosed |
| WO-1993012656-A1 | METHOD FOR CONTROLLING INSECTS | MICHIGAN STATE UNIVERSITY (US) | 1993-07-08 | — | — | WO | disclosed |