SCHEMBL9397237

SCHEMBL9397237

O=c1cc(S)n([C@H]2O[C@@H](COP(=O)(O)O)C(O)C2O)c(=O)[nH]1

nearest known ligand 0.76

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 8/20 0.60
UMPS P11172 4/20 0.60
DNPH1 O43598 1/20 0.53
P2RY6 Q15077 6/20 0.52
P2RY4 P51582 3/20 0.51
P2RY14 Q15391 2/20 0.50
P2RX3 P56373 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29560042 0.91 P2RY2 (0.72) P2RY2P2RY6P2RY4P2RY14P2RX3
SCHEMBL12727821 0.87 P2RY2 (0.61) P2RY2UMPSDNPH1P2RY6P2RY4
SCHEMBL2130675 0.87 P2RY2 (0.61) P2RY2UMPSDNPH1P2RY6P2RY4
SCHEMBL12143118 0.86 P2RY2 (0.63) P2RY2UMPSDNPH1P2RY6P2RY4
SCHEMBL12143119 0.86 UMPS (0.65) P2RY2UMPSDNPH1P2RY6P2RY4
SCHEMBL15522444 0.86 P2RY2 (0.63) P2RY2UMPSDNPH1P2RY6P2RY4
SCHEMBL15196259 0.86 P2RY2 (0.63) P2RY2UMPSDNPH1P2RY6P2RY4
SCHEMBL15196242 0.86 P2RY2 (0.63) P2RY2UMPSDNPH1P2RY6P2RY4
SCHEMBL1364786 0.86 UMPS (0.65) P2RY2UMPSDNPH1P2RY6P2RY4
SCHEMBL1363428 0.86 P2RY2 (0.63) P2RY2UMPSDNPH1P2RY6P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5298614-A Molecular size distribution of rebonucleic acid NIPPON SHINYAKU CO. LTD. (JP) 1994-03-29 US disclosed