Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20916328 | 0.80 | KDM4E (0.38) | KDM4EALOX12LMNAMAPTHTT | |
| SCHEMBL23714073 | 0.80 | KDM4E (0.45) | KDM4EALOX12SLC40A1LMNAMAPT | |
| SCHEMBL481403 | 0.80 | KDM4E (0.56) | KDM4EALOX12LMNAMAPTHTT | |
| Water SCHEMBL3453996 | 0.79 | KDM4E (0.54) | KDM4EALOX12LMNAMAPTHTT | |
| SCHEMBL9196476 | 0.76 | KMT2A (0.41) | XPO1SLC40A1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8645713 | 0.75 | KDM4E (0.59) | KDM4EALOX12SLC40A1LMNAMAPT | |
| SCHEMBL4563072 | 0.72 | HDAC1 (0.46) | AKR1B1HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7555208 | 0.71 | NCF1 (0.45) | KDM4ELMNAMAPTALDH1A1KMT2A | |
| SCHEMBL8847325 | 0.71 | TSHR (0.42) | KDM4EALOX12LMNAMAPTHTT | |
| SCHEMBL9179403 | 0.71 | TSHR (0.43) | MAPTSMN1; SMN2ALDH1A1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |