SCHEMBL9397305

SCHEMBL9397305

CCCC1C=COC(O)C1=O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KAT2A Q92830 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15583 0.70
SCHEMBL6288737 0.68
SCHEMBL17595307 0.62 CYP1A2 (0.30)
Tetrahydrofuran SCHEMBL8329821 0.61 FUCA1 (0.33)
Iodide SCHEMBL11560630 0.60
SCHEMBL3774613 0.58
SCHEMBL6439905 0.56
SCHEMBL27483872 0.56 NFKB1 (0.32)
SCHEMBL10627324 0.56 PPARG (0.37) KAT2A
SCHEMBL665389 0.56 CYP1A2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0452809-B1 A therapeutic agent for pollakiuria, urinary urgency or incontinence of urine comprising alpha-phenyl-alpha-pyridylalkanoic acid derivatives FUJISAWA PHARMACEUTICAL CO (JP) 1994-07-27 EP disclosed
US-5202331-A THERAPEUTIC AGENT FOR DYSURIA COMPRISING ALPHA-PHENYL-ALPHA-PYRIDYLALKANOIC ACID DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-04-13 US disclosed
EP-0452809-A2 A therapeutic agent for pollakiuria, urinary urgency or incontinence of urine comprising alpha-phenyl-alpha-pyridylalkanoic acid derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-10-23 EP disclosed