Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397645 | 1.00 | GSTP1 (0.37) | GSTP1HCAR2ATMLMNAPOLB | |
| SCHEMBL30849893 | 0.82 | MAPK1 (0.43) | GSTP1HCAR2ATMLMNAPOLB | |
| SCHEMBL7550109 | 0.82 | ALDH1A1 (0.34) | POLBMAPK1ALDH1A1TP53CYP3A4 | |
| SCHEMBL9004563 | 0.80 | GSTP1 (0.38) | GSTP1HCAR2ATMLMNAPOLB | |
| SCHEMBL21636809 | 0.80 | GSTP1 (0.38) | GSTP1HCAR2ATMLMNAPOLB | |
| SCHEMBL10943665 | 0.80 | GSTP1 (0.38) | GSTP1HCAR2ATMLMNAPOLB | |
| SCHEMBL29162998 | 0.78 | GSTP1 (0.37) | GSTP1HCAR2ATMLMNAPOLB | |
| SCHEMBL21112017 | 0.78 | HTT (0.45) | GSTP1HCAR2ATMLMNAPOLB | |
| SCHEMBL6249926 | 0.78 | GSTP1 (0.37) | GSTP1HCAR2ATMLMNAPOLB | |
| SCHEMBL9329189 | 0.77 | ALDH1A1 (0.53) | GSTP1HCAR2ATMLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324786-A | Process for preparation of a solid phase system | ORPEGEN MEDIZINISCHE-MOLEKULAR BIOLOGISCHE FORSCHUNGSGESELLSCHAFT MBH (DE) | 1994-06-28 | — | — | US | disclosed |
| US-5214195-A | ALLYL ESTERS AND THE USE THEREOF FOR THE BUILD-UP OF SOLID PHASE SYSTEMS FOR SOLID PHASE REACTIONS | ORPEGEN MEDIZINISCH-MOLEKULAR BIOLOGISCHE FORSCHUNGSGESELLSCHAFT MBH (DE) | 1993-05-25 | — | — | US | disclosed |
| EP-0415331-A2 | Allyl esters and their application to the construction of solid phase systems for solid phase reactions | Orpegen Medizinisch-Molekularbiologische Forschungsgesellschaft m.b.H. (DE) | 1991-03-06 | — | — | EP | disclosed |