Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | KCNE1 | P15382 | 11/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 11/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813939 | 1.00 | KDM4E (0.64) | KDM4EKCNE1KCNQ1CYP3A4ALOX15 | |
| SCHEMBL9397720 | 0.84 | KDM4E (0.46) | KDM4EKCNE1KCNQ1CYP3A4ALOX15 | |
| SCHEMBL9397730 | 0.84 | KDM4E (0.46) | KDM4EKCNE1KCNQ1CYP3A4ALOX15 | |
| SCHEMBL9397708 | 0.84 | KDM4E (0.46) | KDM4EKCNE1KCNQ1CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL11611521 | 0.84 | KCNE1 (0.48) | KDM4EKCNE1KCNQ1CYP3A4ABCC9 | |
| Hydrochloric Acid SCHEMBL11611531 | 0.84 | KCNE1 (0.48) | KDM4EKCNE1KCNQ1CYP3A4ABCC9 | |
| Hydrochloric Acid SCHEMBL11611527 | 0.84 | KCNE1 (0.48) | KDM4EKCNE1KCNQ1CYP3A4ABCC9 | |
| SCHEMBL9398509 | 0.81 | KDM4E (0.68) | KDM4EKCNE1KCNQ1CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL11611584 | 0.81 | KCNE1 (0.46) | KDM4EKCNE1KCNQ1CYP3A4ABCC9 | |
| Hydrochloric Acid SCHEMBL11611577 | 0.81 | KCNE1 (0.46) | KDM4EKCNE1KCNQ1CYP3A4ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318969-A | Hypotensive, vasodilating action and muscle relaxants | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0339562-B1 | BENZOPYRAN COMPOUND AND ITS PHARMACEUTICAL USE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-5143936-A | Benzopyran compound and its pharmaceutical use | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| EP-0339562-A1 | Benzopyran compound and its pharmaceutical use | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-11-02 | — | — | EP | disclosed |