Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 11/20 | 0.64 |
| ▸ | ABCC9 | O60706 | 8/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397702 | 0.86 | ABCB1 (0.72) | ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL9398637 | 0.86 | ABCB1 (0.72) | ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL9397785 | 0.86 | ABCB1 (0.72) | ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL9398425 | 0.83 | ABCB1 (0.62) | ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL9397689 | 0.83 | CYP3A4 (0.65) | ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL9269639 | 0.83 | ABCB1 (0.70) | ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL9269632 | 0.83 | ABCB1 (0.70) | ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL9269643 | 0.83 | ABCB1 (0.70) | ABCB1ABCC9CYP3A4ALOX15 | |
| SCHEMBL9272734 | 0.82 | ABCC9 (0.67) | ABCB1ABCC9 | |
| SCHEMBL9272726 | 0.82 | ABCC9 (0.67) | ABCB1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318969-A | Hypotensive, vasodilating action and muscle relaxants | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0339562-B1 | BENZOPYRAN COMPOUND AND ITS PHARMACEUTICAL USE | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-5143936-A | Benzopyran compound and its pharmaceutical use | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-09-01 | — | — | US | disclosed |