Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | THRB | P10828 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | RECQL | P46063 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | APEX1 | P27695 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397885 | 0.90 | CYP1A2 (0.39) | CYP1A2KDM4EMEN1CYP3A4THRB | |
| SCHEMBL28193525 | 0.85 | ALDH1A1 (0.42) | CYP1A2KDM4EMEN1CYP3A4THRB | |
| SCHEMBL28005645 | 0.80 | CYP1A2 (0.39) | CYP1A2KDM4EMEN1CYP3A4THRB | |
| SCHEMBL28059251 | 0.78 | CYP1A2 (0.39) | CYP1A2KDM4EMEN1CYP3A4THRB | |
| SCHEMBL28011471 | 0.78 | AURKA (0.39) | CYP1A2KDM4EMEN1CYP3A4THRB | |
| SCHEMBL3822788 | 0.77 | AURKA (0.42) | CYP1A2KDM4EMEN1CYP3A4THRB | |
| SCHEMBL30218795 | 0.77 | AURKA (0.42) | CYP1A2KDM4EMEN1CYP3A4THRB | |
| SCHEMBL27999679 | 0.76 | AURKA (0.41) | CYP1A2KDM4EMEN1CYP3A4THRB | |
| SCHEMBL27842341 | 0.76 | AURKA (0.41) | CYP1A2KDM4EMEN1CYP3A4THRB | |
| Water SCHEMBL28058241 | 0.76 | AURKA (0.41) | CYP1A2KDM4EMEN1CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361894-B1 | Loading and controlled release of amphiphatic molecules to and from liposomes | YISSUM RES DEV CO (IL) | 1994-11-09 | — | — | EP | disclosed |
| US-5316771-A | Drug delivery | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1994-05-31 | — | — | US | disclosed |
| US-5192549-A | Ammonium gradient, sustained release, doxorubicin, acridine orange | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1993-03-09 | — | — | US | disclosed |
| EP-0361894-A2 | Loading and controlled release of amphiphatic molecules to and from liposomes | YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1990-04-04 | — | — | EP | disclosed |