Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | KDM4B | O94953 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398237 | 1.00 | ALDH1A1 (0.53) | ALDH1A1CYP3A4ALOX15TDP1TSHR | |
| SCHEMBL31607968 | 0.83 | CYP19A1 (0.57) | ALDH1A1CYP19A1MAOAMAOBBACE1 | |
| SCHEMBL9798526 | 0.79 | TSHR (0.52) | ALDH1A1CYP3A4ALOX15TDP1TSHR | |
| SCHEMBL9798531 | 0.79 | TSHR (0.52) | ALDH1A1CYP3A4ALOX15TDP1TSHR | |
| SCHEMBL28231121 | 0.79 | ALDH1A1 (0.60) | ALDH1A1CYP3A4ALOX15TDP1TSHR | |
| SCHEMBL2688564 | 0.77 | ALDH1A1 (0.59) | ALDH1A1CYP3A4ALOX15TDP1TSHR | |
| SCHEMBL1603757 | 0.77 | BACE1 (0.57) | RECQLKDM4AKDM4BBACE1APP | |
| SCHEMBL1603756 | 0.77 | BACE1 (0.57) | RECQLKDM4AKDM4BBACE1APP | |
| SCHEMBL9798426 | 0.75 | TDP1 (0.51) | ALDH1A1CYP3A4ALOX15TDP1TSHR | |
| SCHEMBL9798422 | 0.75 | TDP1 (0.51) | ALDH1A1CYP3A4ALOX15TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5357015-A | Glow discharge crosslinking of polysiloxane sol-gel glass or film | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS (US) | 1994-10-18 | — | — | US | claimed |